Mixing Vivitrol and alcohol can be risky, and in some cases, counterproductive to recovery. While highly effective when taken as prescribed, drinking alcohol while on Vivitrol can undermine its benefits, increase health risks, and slow your progress toward sobriety.
In this guide, we’ll break down what Vivitrol is, how it works, and the potential dangers of mixing it with alcohol, so you can make informed decisions about your recovery journey.
What Is Vivitrol?
Vivitrol is the brand name for extended-release naltrexone, a prescription medication used to treat alcohol use disorder and opioid dependence. Unlike oral naltrexone, which must be taken daily, Vivitrol is administered as a monthly intramuscular injection in a healthcare setting, ensuring consistent blood levels and improving treatment adherence.
As an opioid antagonist, Vivitrol binds to and blocks opioid receptors in the brain. This prevents opioids from producing their euphoric and pain-relieving effects and reduces alcohol cravings by dampening the brain’s reward response to drinking.
Vivitrol is most effective when combined with a comprehensive addiction treatment plan that includes counseling, behavioral therapies, peer support groups, and medical monitoring. It is typically prescribed after a patient has fully detoxed from opioids (to avoid precipitated withdrawal) or after an initial period of alcohol abstinence.
Here are some risks when you drink alcohol while on Vivitrol:
Reduced Effectiveness in Treating Alcohol Dependence
Drinking alcohol while on Vivitrol undermines its primary goal, helping you stay sober. Although Vivitrol blocks opioid receptors, it does not prevent alcohol from affecting other brain pathways, meaning you can still become intoxicated. This can weaken motivation for recovery, increase the risk of relapse, and disrupt the progress made during treatment.
Increased Risk of Liver Damage
Both alcohol and Vivitrol are metabolized by the liver. When combined, they can intensify liver stress, particularly in people with pre-existing liver conditions or a history of heavy drinking. This can interfere with the body’s ability to maintain a cleansing liver function, leading to toxin buildup and worsening overall health. Elevated liver enzymes, jaundice (yellowing of the skin or eyes), dark urine, and abdominal pain are warning signs that require immediate medical attention.
Heightened Side Effects and Health Risks
Mixing alcohol with Vivitrol can amplify side effects such as nausea, dizziness, fatigue, and headaches. Alcohol also impairs judgment, balance, and reaction time, which, when combined with these side effects, increases the risk of accidents, falls, and other injuries. Over time, continued drinking on Vivitrol can contribute to serious conditions like high blood pressure, cardiovascular strain, and cognitive decline.
For individuals struggling to stop drinking while on Vivitrol, seeking professional help through a professional alcohol detox program can provide the structure, counseling, and medical oversight needed to break the cycle. Always inform your healthcare provider about all prescription drugs, over-the-counter medications, and supplements you are using before starting Vivitrol to avoid harmful interactions.
Other Medications to Avoid While Taking Vivitrol
- Opioid pain relievers (e.g., hydrocodone, methadone): These will be ineffective due to Vivitrol’s opioid-blocking effects and can be dangerous if attempted in high doses to “override” the block.
- Opioid-based cough or cold medicine (e.g., codeine combinations): These medications won’t work properly and may cause harmful interactions.
- Opioid antagonists for constipation (e.g., methylnaltrexone, naloxegol): These can intensify side effects when taken with Vivitrol.
Is Vivitrol Addictive?
Vivitrol is non-addictive and does not produce a high, cravings, or withdrawal symptoms. It works purely by blocking the pleasurable effects of alcohol and opioids, helping individuals maintain sobriety without creating a new dependence. Because it does not activate opioid receptors, it has no abuse potential and does not cause physical dependence.
However, it is not a stand-alone cure, Vivitrol should be used alongside therapy, medical supervision, and lifestyle changes for the best long-term results.
Final Thoughts from Guidance Detox & Rehab
Mixing alcohol with Vivitrol is never worth the risk. While Vivitrol can be a powerful tool in preventing relapse and supporting sobriety, drinking while on the medication can undermine its benefits, strain your liver, and increase the chances of setbacks in recovery. The most effective outcomes come when Vivitrol is paired with a comprehensive treatment plan, medical supervision, and a strong commitment to a sober lifestyle.
At Guidance Detox & Rehab, we provide premier inpatient rehab programs in Utah that include medically supervised detox, evidence-based therapy, and alcohol addiction treatment tailored to each individual. Our approach combines behavioral therapy, medication-assisted treatment, family involvement, and relapse prevention planning to give you the best possible chance at lasting recovery. With early intervention, proper medication management, and a supportive environment, you can achieve long-term sobriety and regain control over your life.
